Publication
A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling
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The identification of a conserved triple-serine motif in the SorCS2 receptor that functions as a molecular switch for BDNF-induced neurotrophic signalling
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Findings demonstrating that phosphomimetic variants of this motif can activate CREB and induce neurite branching independently of BDNF
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The utilisation of ioGlutamatergic Neurons to validate intracellular signalling mechanisms and SorCS2-mediated neuronal differentiation