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Discover ioCells

Discover ioCells

Programmed identity
in every cell

Human iPSC-derived cells powered by opti-ox, consistency and scalability are built-in.

Mature, functional human
iPSC-derived cells within days,
powered by opti-ox

The future of human health will be defined by technologies that accelerate the world's access to more effective medicines.

Human cells are a cornerstone of fundamental disease research, drug discovery, and clinical translation. Yet, despite decades of research into iPSCs, emerging cures for some of the world鈥檚 most pervasive diseases have been bottlenecked by a lack of access to standardised, easy to use and readily accessible human cells.

We built ioCells to solve this challenge.

Developed on our platform, and powered by opti-ox technology, ioCells are human cells deterministically programmed from iPSCs consistently, at scale. With ioCells, scientists no longer need to battle with variance, unreliability, physiological irrelevance and long experimental timelines. Instead, scientists can finally focus on the next great advances in human health.

ioCells are for research use only.

Browse ioCells portfolio

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ioWild Type Cells

ioWild Type Cells are defined, easy-to-use, functional iPSC-derived human cells from a healthy donor background that are ready for fundamental research and drug discovery experimentation within days.

Discover ioCells portfolio ICC ioDisease model cells

ioDisease Model Cells

ioDisease Model Cells are ioWild Type Cells engineered to contain disease-relevant mutations. ioDisease Model Cells and ioWild Type Cells form an isogenic pair allowing scientists to make true comparisons.

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CRISPR-Ready ioCells

CRISPR-Ready ioCells are human iPSC-derived cells constitutively expressing Cas9 nuclease for rapid gene knockout generation. 

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ioTracker Cells

ioTracker Cells are human iPSC-derived cells constitutively expressing a fluorescent protein for easy visualisation, tracking, and isolation of human cells in live-cell imaging assays.

Benchtop benefits

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Consistent

Our platform ensures consistency between every batch of cells, overcoming the challenge of data reproducibility.

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Cost-effective

ioCells generate quality data at industry leading seeding densities. You can do more with every vial as every well saves you money.

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Defined

Every ioCell has its identity characterised by ICC, RT-qPCR and RNA-Seq at minimum.

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Easy-to-use

ioCells are delivered cryopreserved and require a simple protocol using an open-source medium to get started.

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Quick

Deterministically programmed cells mature rapidly, meaning cells are ready for experimentation and data gathering within days post-revival.

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Scalable

With opti-ox technology we can make billions of consistently programmed cells, surpassing the demands of industrial workflows.

What Scientists Say About ioCells

An image of Dr Marijn Vlaming

Dr Marijn Vlaming

Head of Biology - Beerse & Leiden | Charles River

"Using more relevant cell models such as ioCells from 糖心原创 helps us to test safety and toxicity in vitro, in parallel with efficacy, and as such we will be able to identify the safe or unsafe drug candidates very early in the drug discovery process"

An image of Dr Mariangela Iovino

Dr Mariangela Iovino

Senior Group Leader | Biology Discovery | Charles River

鈥淭hese cells were really easy-to-use and ready to be plated in the assay format"

An image of Rodney A. Bowling Jr, PhD

Rodney A. Bowling Jr, PhD

Co-Founder & Chief Scientific Officer | Everlum Bio

"I found the customer service at 糖心原创 to be a premium, I found it to be wonderful鈥

Our deterministic cell programming technology

 

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Every ioCell is powered by opti-ox.


Using opti-ox, populations of stem cells are precisely and consistently programmed into a chosen cell identity. Each vial of ioCells contains a defined and highly characterised population of iPSC-derived human cells that are ready for quality data production in a matter of days. Their high lot-to-lot consistency provides a reliable cell model that enables scientists to conduct repeatable and scalable experiments in drug discovery and disease research. 

Product resources

Related pages

Our platform Discover the cell coding platform behind our cells
Resources Explore our latest scientific insights, webinars, blogs and videos
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